{"id":5307,"date":"2024-03-26T11:59:15","date_gmt":"2024-03-26T11:59:15","guid":{"rendered":"https:\/\/integratedcarejournal.com\/?p=5307"},"modified":"2024-03-26T13:38:59","modified_gmt":"2024-03-26T13:38:59","slug":"optimising-doac-therapy-collaborative-approach-improved-patient-care-cost-efficiency","status":"publish","type":"post","link":"https:\/\/integratedcarejournal.com\/optimising-doac-therapy-collaborative-approach-improved-patient-care-cost-efficiency\/","title":{"rendered":"Optimising DOAC Therapy: A collaborative approach to improved patient care and cost efficiency"},"content":{"rendered":"

Spirit Health<\/h3>\n

As an independent service provider to the NHS for over 15 years, Spirit Health do things differently. We specialise in partnering with NHS Medicines Optimisation teams to provide products and clinical services that help deliver cost efficiencies and quality improvements in patient outcomes.<\/p>\n


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The situation<\/h3>\n

Direct-acting oral anticoagulants (DOACs) are widely recognised as alternative anticoagulants<\/a> to prevent strokes in patients with Atrial Fibrillation (AF). There are four DOACs available; the aim was to optimise care for all patients prescribed a DOAC for NV-AF and to review patients prescribed apixaban to see if a lower-cost alternative could be used. When the work was undertaken, apixaban was the highest-costing drug to the NHS<\/a> in England in the 2022\/23 period.<\/p>\n

The issue is that stroke and bleeding risks change over time<\/a>, so medication needs to be reviewed annually. This requires high levels of collaboration between primary and secondary care to review all eligible patient medication for drug interactions, over-the-counter medications and herbal\/alternative therapies.<\/p>\n

The opportunity was to optimise the quality of care for patients on a DOAC across a locality and review if an alternative lower-priced DOAC was suitable. Carried out between October 2022 to May 2023, the work would ensure patients were on the appropriate DOAC and dose regime for their renal function, liver function, weight, co-morbidities, and medication to ensure optimal oral anticoagulant (OAC) therapy.<\/p>\n


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Objective<\/h3>\n

The main objectives were to optimise care for all patients prescribed a DOAC for NV-AF and to review patients’ prescribed apixaban to see if a lower-cost alternative could be used.<\/p>\n

The Spirit Active Implementation\u2122 team identified all patients on existing DOAC therapy, checking patient eligibility to change through up-to-date patient blood records, calculating Creatinine Clearance, CHA2DS2-VASc7 and HAS-BLED\/ORBIT scores. They also discussed any patients with incorrect doses\/significant interactions\/safety concerns or identified issues with the appropriate clinician.<\/p>\n

To fulfil the objectives, the project required continual collaboration between the Spirit Active Implementation\u2122 team with multiple GP practice staff, secondary care HCPs, and multiple stakeholders across the locality.<\/p>\n

The review service not only highlighted those who were eligible to be switched to a lower-cost DOAC alternative but also identified:<\/p>\n